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Roles of Sex Hormones and Gender in the Gut Microbiota

Molecular pathway of estrogen receptor (ER) action. Typically, estrogen binds to the ligand-binding domain of receptors in the nucleus, which causes a conformational change. Estrogen-responsive elements (ERE) mediate genomic effects. RE, response element; TF, transcription factor; GF, growth factor; GF-R, growth factor receptor; CoA, co-activator; CoR, co-repressor; MAPK, mictogen-activated protein kinase; PI3K, phophoinositide 3-kinase; Src, proto-oncogene tyrosine-protein kinase; AP-1, activating protein-1; Sp-1, stimulating protein-1. Adapted from Nie et al.¹⁶
Variations in Clinical Practice of Esophageal High-resolution Manometry: A Nationwide Survey

Measurement parameters utilized to determine the esophageal motor function. (A) Esophagogastric junction (EGJ). (B) Esophageal body. EGJ-CI, esophagogastric junction-contractile integral; IRP, integrated relaxation pressure; LES, lower esophageal sphincter.
Normal Values of High-resolution Manometry Parameters With Provocative Maneuvers

High-resolution manometry test swallows and maneuvers. (A) Supine 5 mL liquid; (B) upright 5 mL liquid; (C) viscous (apple sauce); (D) solid (graham cracker); (E) multiple rapid swallow; and (F) rapid drink challenge. Integrated relaxation pressure (IRP) and distal contractile integral (DCI) were 11 mmHg and 1760 mmHg·cm·sec (A), 8 mmHg and 1950 mmHg·cm·sec (B), 7 mmHg and 1600 mmHg·cm·sec (C), 10 mmHg and 1400 mmHg·cm·sec (D), 4 mmHg and 4600 mmHg·cm·sec (E), and 3 mmHg and 0 mmHg·cm·sec (F), respectively. Figure used with permission from the Esophageal Center at Northwestern.
Rectosigmoid Localization of Radiopaque Markers for Identifying Defecation Disorders in Patients With Chronic Constipation: A Retrospective Cohort Study

Our diagnostic algorithm of defecation disorders using a colonic transit study. DD, defecation disorders; DRE, digital rectal examination; NTC, normal transit constipation; STC, slow transit constipation; RS, rectosigmoid colon.
Inter-hemispheric Functional Connections Are More Vulnerable to Attack Than Structural Connection in Patients With Irritable Bowel Syndrome

Statistical maps showing voxel-mirrored homotopic connectivity (VMHC) differences between irritable bowel syndrome (IBS) and healthy controls (HCs; P < 0.05, corrected with Alphasim). IBS patients showed much higher VMHC in superior occipital gyrus, middle occipital gyrus, precuneus, posterior cingulate gyrus, and angular gyrus (red), while lower in supplementary motor area (blue). The color bar indicates the T-value from t test between groups.

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J Neurogastroenterol Motil 2021; 27(3): 307~443 Total PDF

Editorials

Analysis of Whole Gut Motility for the Evaluation of Diabetic Gastroenteropathy: Still the Road Untraveled?

Eun Jeong Gong

J Neurogastroenterol Motil 2021; 27(3): 307-309 https://doi.org/10.5056/jnm21114

Role of Bile Reflux in Functional Dyspepsia: Areas That Need Further Research

Seung Joo Kang

J Neurogastroenterol Motil 2021; 27(3): 310-311 https://doi.org/10.5056/jnm21112

Is There a Role for Radiopaque Markers in Identifying Defecation Disorders?

Yoo Jin Lee

J Neurogastroenterol Motil 2021; 27(3): 312-313 https://doi.org/10.5056/jnm21115

Reviews

Roles of Sex Hormones and Gender in the Gut Microbiota

Kichul Yoon and Nayoung Kim

J Neurogastroenterol Motil 2021; 27(3): 314-325 https://doi.org/10.5056/jnm20208

The Usefulness of Symptom-based Subtypes of Functional Dyspepsia for Predicting Underlying Pathophysiologic Mechanisms and Choosing Appropriate Therapeutic Agents

Kwang Jae Lee

J Neurogastroenterol Motil 2021; 27(3): 326-336 https://doi.org/10.5056/jnm21042

Emergence of Celiac disease and Gluten-related disorders in Asia

Srikant Mohta, Mahendra S Rajput, Vineet Ahuja, and Govind K Makharia

J Neurogastroenterol Motil 2021; 27(3): 337-346 https://doi.org/10.5056/jnm20140

Original Articles

Variations in Clinical Practice of Esophageal High-resolution Manometry: A Nationwide Survey

Eun Jeong Gong, Soo In Choi, Bong Eun Lee, Yang Won Min, Yu Kyung Cho, Kee Wook Jung, Ji Hyun Kim, and Moo In Park; Dysphagia Study Group Under the Korean Society of Neurogastroenterology and Motility

J Neurogastroenterol Motil 2021; 27(3): 347-353 https://doi.org/10.5056/jnm20217

Normal Values of High-resolution Manometry Parameters With Provocative Maneuvers

Hui Su, Amanda J Krause, Melina Masihi, Jacqueline Prescott, Alex Decorrevont, Emma Germond, Dave Karasik, Wenjun Kou, John E Pandolfino, and Dustin A Carlson

J Neurogastroenterol Motil 2021; 27(3): 354-362 https://doi.org/10.5056/jnm20118

Upright Integrated Relaxation Pressure Predicts Symptom Outcome for Esophagogastric Junction Outflow Obstruction

Songfeng Chen, Mengya Liang, Niandi Tan, Mengyu Zhang, Yuqing Lin, Peixian Cao, Qianjun Zhuang, and Yinglian Xiao

J Neurogastroenterol Motil 2021; 27(3): 363-369 https://doi.org/10.5056/jnm20106

Seago Stretch Large Sofa Slipcovers Print Sofa Cover Fitted Couc

Shohei Sumi, Norihisa Ishimura, Hironobu Mikami, Eiko Okimoto, Yuji Tamagawa, Tsuyoshi Mishiro, Yoshikazu Kinoshita, and Shunji Ishihara

J Neurogastroenterol Motil 2021; 27(3): 370-376 https://doi.org/10.5056/jnm20115

The Reflux Symptoms Before and After Peroral Endoscopic Myotomy of Chinese Patients With Achalasia

Ying Xu, Yan Wang, Yun Bao, Ting Yu, Yurong Tang, Lin Lin, and Liuqin Jiang

J Neurogastroenterol Motil 2021; 27(3): 377-389 https://doi.org/10.5056/jnm20041

Gastric Emptying Time and Volume of the Small Intestine as Objective Markers in Patients With Symptoms of Diabetic Enteropathy

Mette W Klinge, Nanna Sutter, Esben B Mark, Anne-Mette Haase, Per Borghammer, Vincent Schlageter, Sten Lund, Jesper Fleischer, Karoline Knudsen, Asbjørn M Drewes, and Klaus Krogh

J Neurogastroenterol Motil 2021; 27(3): 390-399 https://doi.org/10.5056/jnm19195

Bile Reflux Gastropathy and Functional Dyspepsia

Andrew Lake, Satish S C Rao, Sebastian Larion, Helena Spartz, and Sravan Kavuri

J Neurogastroenterol Motil 2021; 27(3): 400-407 https://doi.org/10.5056/jnm20102

Predictors of Early Readmissions in Hospitalized Patients With Gastroparesis: A Nationwide Analysis

Ravi B Pavurala, Peter P Stanich, Somashekar G Krishna, Praveen Guturu, Alice Hinton, Darwin L Conwell, and Gokulakrishnan Balasubramanian

J Neurogastroenterol Motil 2021; 27(3): 408-418 https://doi.org/10.5056/jnm20105

Rectosigmoid Localization of Radiopaque Markers for Identifying Defecation Disorders in Patients With Chronic Constipation: A Retrospective Cohort Study

Tatsuya Abe, Masao Kunimoto, Yoshikazu Hachiro, Kei Ohara, Mitsuhiro Inagaki, and Masanori Murakami

J Neurogastroenterol Motil 2021; 27(3): 419-425 https://doi.org/10.5056/jnm20204

Inter-hemispheric Functional Connections Are More Vulnerable to Attack Than Structural Connection in Patients With Irritable Bowel Syndrome

Guangyao Liu, Shan Li, Nan Chen, Ziyang Zhao, Man Guo, Hong Liu, Jie Feng, Dekui Zhang, Zhijun Yao, and Bin Hu

J Neurogastroenterol Motil 2021; 27(3): 426-435 https://doi.org/10.5056/jnm20134

Letter to the Editor

A Novel Cohesinopathy Causing Chronic Intestinal Pseudo Obstruction in 2 Siblings and Literature Review

Vybhav Venkatesh, Aradhana Aneja, Keerthivasan Seetharaman, Neha Anushree, Surinder S Rana, and Sadhna B Lal

J Neurogastroenterol Motil 2021; 27(3): 436-437 https://doi.org/10.5056/jnm20259

Metastatic Intrahepatic Cholangiocarcinoma Presenting as an Achalasia-like Syndrome

Catarina Gomes, João Correia, Ana Ponte, Edgar Afecto, Rolando Pinho, and João Carvalho

J Neurogastroenterol Motil 2021; 27(3): 438-439 https://doi.org/10.5056/jnm21035

Erratum, Corrigendum, and Addendums

Erratum

J Neurogastroenterol Motil 2021; 27(3): 440-440 Dorman 47076 Vacuum Amplifier

Corrigendum

J Neurogastroenterol Motil 2021; 27(3): 441-442 https://doi.org/10.5056/jnm20014C

Addendum

J Neurogastroenterol Motil 2021; 27(3): 443-443 https://doi.org/10.5056/jnm18029A

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: Current Issue

July 2021
Volume 27
Issue 3

News & Notice

Best Reviewers 2020

Tae Hee Lee
Institute for Digestive Research, Soonchunhyang University Seoul Hospital, Seoul, Korea

Yu Kyung Cho
Department of Internal Medicine, The Catholic University of Korea, Seoul St. Mary’s hospital, Seoul, Korea
Jung Ho Park
Departments of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University College of Medicine, Seoul, Korea

Uday C Ghoshal
Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India
Kewin T H Siah
Division of Gastroenterology and Hepatology, Department of Medicine, National University Hospital, Singapore

Official Journal of

The aim of the Journal is to foster and promote research activities on the area of the motor, sensory and functional disorders of gastrointestinal tract. The Journal provides researchers with accessible rooms for publication of their research results in the field of neuroga- stroenterology and motility.

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No.	Cited items	Category	Citations
1	What Is New in Rome IV Max J Schmulson, and Douglas A Drossman. Journal of Neurogastroenterology and Motility. 2017 May; 23(2): 151-163.	Review	219
2	Mosquito Barrier Natural Outdoor Insect Pest Repellent - 1 Gal Karol Kowalski, and Agata Mulak. J Neurogastroenterol Motil. 2019 Jan; 25(1): 48-60.	Review	202
3	Pharmacokinetics and Pharmacodynamics of the Proton Pump Inhibitors Jai Moo Shin, and Nayoung Kim. Journal of Neurogastroenterology and Motility. 2013 Jan; 19(1): 25-35.	Review	173
4	Biopsychosocial Model of Irritable Bowel Syndrome Yukari Tanaka, Motoyori Kanazawa, Shin Fukudo and Douglas A Drossman. J Neurogastroenterol Motil. 2011 Apr; 17(2): 131-139.	Review	157
5	Epidemiology of Gastroesophageal Reflux Disease in Asia: A Systematic Review Hye-Kyung Jung. J Neurogastroenterol Motil. 2011 Jan; 17(1): 14-27.	Review	136
6	Modulatory Effects of Gut Microbiota on the Central Nervous System: How Gut Could Play a Role in Neuropsychiatric Health and Diseases Shadi S Yarandi, Daniel A Peterson, Glen J Treisman, Timothy H Moran, and Pankaj J Pasricha. J Neurogastroenterol Motil. 2016 Apr; 22(2): 201-212.	Review	129
6	Effect of Probiotics on Central Nervous System Functions in Animals and Humans: A Systematic Review Huiying Wang, In-Seon Lee, Christoph Braun, and Paul Enck. Journal of Neurogastroenterology and Motility. 2016 Oct; 22(4): 589-605.	Review	129
8	Achalasia Cardia Subtyping by High-Resolution Manometry Predicts the Therapeutic Outcome of Pneumatic Balloon Dilatation Nitesh Pratap, Rakesh Kalapala, Santosh Darisetty, Nitin Joshi, Mohan Ramchandani, Rupa Banerjee, Sandeep Lakhtakia, Rajesh Gupta, Manu Tandan, G V Rao and D Nageshwar Reddy. J Neurogastroenterol Motil. 2011 Jan; 17(1): 48-53.	Original Article	127
9	How to Interpret Hydrogen Breath Tests Uday C Ghoshal. J Neurogastroenterol Motil. 2011 Jul; 17(3): 312-317.	How to Interpret a Functional or Motility Test	123
10	The Immune System in Irritable Bowel Syndrome Giovanni Barbara, Cesare Cremon, Giovanni Carini, Lara Bellacosa, Lisa Zecchi, Roberto De Giorgio, Roberto Corinaldesi and Vincenzo Stanghellini. J Neurogastroenterol Motil. 2011 Oct; 17(4): 349-359.	Review	119

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Roles of Sex Hormones and Gender in the Gut Microbiota

Variations in Clinical Practice of Esophageal High-resolution Manometry: A Nationwide Survey

Normal Values of High-resolution Manometry Parameters With Provocative Maneuvers

Rectosigmoid Localization of Radiopaque Markers for Identifying Defecation Disorders in Patients With Chronic Constipation: A Retrospective Cohort Study

Inter-hemispheric Functional Connections Are More Vulnerable to Attack Than Structural Connection in Patients With Irritable Bowel Syndrome

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